Follow all directions on your prescription label and read all medication guides or instruction sheets. Use the medicine exactly as directed. If you need major surgery or will be on long-term bed rest, you may need to stop using this medicine for a short time.
Any doctor or surgeon who treats you should know that you are using estradiol and progesterone. Your doctor should check your progress on a regular basis every 3 to 6 months to determine whether you should continue this treatment. Self-examine your breasts for lumps on a monthly basis and have a mammogram every year while using estradiol and progesterone. Take the medicine with food as soon as you can, but skip the missed dose if your next dose is due in less than 2 hours. Do not take two doses at one time.
Avoid smoking. It can greatly increase your risk of blood clots, stroke, or heart attack while using this medicine. Grapefruit may interact with this medicine and lead to unwanted side effects. Avoid the use of grapefruit products. Get emergency medical help if you have signs of an allergic reaction: hives; difficult breathing; swelling of your face, lips, tongue, or throat. This is not a complete list of side effects and others may occur.
Call your doctor for medical advice about side effects. Sometimes it is not safe to use certain medications at the same time. Some drugs can affect your blood levels of other drugs you take, which may increase side effects or make the medications less effective. Many drugs can interact with estradiol and progesterone.
This includes prescription and over-the-counter medicines, vitamins, and herbal products. Not all possible interactions are listed in this medication guide.
Tell your doctor about all your current medicines and any medicine you start or stop using. Remember, keep this and all other medicines out of the reach of children, never share your medicines with others, and use this medication only for the indication prescribed.
Every effort has been made to ensure that the information provided by Cerner Multum, Inc. Estrogen, a steroid hormone, carries physiological messages to body organs and systems. These messages differ for each body organ and system. Estrogen sends messages to the uterus to grow and replace the lining that is shed during the previous menses. The three major naturally occurring estrogens in women are estrone E1 , estradiol E2 , and estriol E3. Estradiol is the predominant estrogen during reproductive years both in terms of absolute serum levels as well as in terms of estrogenic activity.
During menopause, estrone is the predominant circulating estrogen and during pregnancy estriol is the predominant circulating estrogen in terms of serum levels. Though estriol is the most plentiful of the three estrogens it is also the weakest, whereas estradiol is the strongest with a potency of approximately 80 times that of estriol. Creative Diagnostics company provides estrogen antibodies, antigens, elisa kits as follows:. Progesterone is a hormone produced primarily in the ovaries, but also in smaller quantities by the adrenal glands, and in the placenta of pregnant women.
The hormone helps regulate menstruation, prepares the body for pregnancy, and aids in nourishing the uterine environment to support implantation of the fertilized egg, as well as growth of the placenta. Progesterone levels may be monitored through simple blood serum testing if necessary.
The primary function of estrogens is development of female secondary sexual characteristics. These includes breasts, endometrium, regulation of the menstrual cycle etc. In males estrogen helps in maturation of the sperm and maintenance of a healthy libido. Estrogen is responsible for development of the female body and the secondary sexual characters.
It helps decelerate height increase in females during puberty, accelerates burning of body fat and reduces muscle bulk. Estrogens reduce bone resorption and increase bone formation. Progesterone is not available from our food or the environment, so when ovulation ceases and progesterone levels fall, supplementation with natural, bio-identical progesterone may be necessary.
The most common symptoms of menopause, hot flashes, mood swings, irritability, insomnia, poor concentration, weight gain, bloating and fatigue may actually be a result of excess estrogen and may be relieved with progesterone. The physiological effects of natural progesterone in menopausal women include the following:.
When not balanced with enough progesterone, estrogen can be a potent and dangerous hormone. Excess estrogen can increase the risk of breast cancer and reproductive cancers. While progesterone does have an anti-cancer effect, it also provides benefits to all cells in the body including the brain, heart, nerves, skin and bones.
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